Carbonic anhydrase inhibitor 2

• CAT Number: I044080
• CAS Number: 2758231-43-3
• Molecular Formula: C12H16N4O6S
• Molecular Weight: 344.34
• Purity: ≥95%
• Synonyms: methyl 2-[[2-[(4-sulfamoylphenyl)carbamoylamino]acetyl]amino]acetate
• InChI: InChI=1S/C12H16N4O6S/c1-22-11(18)7-14-10(17)6-15-12(19)16-8-2-4-9(5-3-8)23(13,20)21/h2-5H,6-7H2,1H3,(H,14,17)(H2,13,20,21)(H2,15,16,19)
• InChIKey: HYGAYYSZXIJQMB-UHFFFAOYSA-N
• SMILES: COC(=O)CNC(=O)CNC(=O)NC1=CC=C(C=C1)S(=O)(=O)N

Carbonic anhydrase inhibitor 1 (compound 7c) is a carbonic anhydrase II inhibitor. Carbonic anhydrase inhibitor 3 reduces the intraocular pressure in glaucomatous rabbits[1].

Reference

[1]. Gioele Vannozzi, et al. One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes. J Med Chem. 2022 Jan 13;65(1):824-837.
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