For research use only. Not for therapeutic Use.
Carboxypeptidase B (Cat No.: I040142) is a metalloprotease enzyme that cleaves basic amino acids (like arginine and lysine) from the carboxyl end of peptides and proteins. It plays a crucial role in protein maturation and regulation, particularly in blood coagulation. Found in pancreatic secretions, carboxypeptidase B is involved in activating digestive enzymes and modulating inflammation. It has potential therapeutic applications in treating conditions like pancreatitis, cancer, and wound healing by influencing protein digestion, immune response, and tissue repair.
| CAS Number | 9025-24-5 |
| Molecular Formula | C31H38N4O7S |
| Purity | ≥95% |
| IUPAC Name | 4-[[1-[[1-[2-[(1-benzylsulfanyl-1-oxo-3-phenylpropan-2-yl)carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid |
| InChI | 1S/C31H38N4O7S/c1-20(32-26(36)15-16-27(37)38)28(39)33-21(2)30(41)35-17-9-14-25(35)29(40)34-24(18-22-10-5-3-6-11-22)31(42)43-19-23-12-7-4-8-13-23/h3-8,10-13,20-21,24-25H,9,14-19H2,1-2H3,(H,32,36)(H,33,39)(H,34,40)(H,37,38) |
| InChIKey | TWURVFFNODFJBJ-UHFFFAOYSA-N |
| SMILES | CC(C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CC2=CC=CC=C2)C(=O)SCC3=CC=CC=C3)NC(=O)CCC(=O)O |
| Reference | [1]. FOLK JE, et al. The kinetics of carboxypeptidase B activity. II. Kinetic parameters of the cobalt and cadmium enzymes. J Biol Chem. 1962 Oct;237:3100-4. [2]. Qian X, et al. Molecular characterization of carboxypeptidase B-like (CPB) in Scylla paramamosain and its role in white spot syndrome virus and Vibrio alginolyticus infection. Fish Shellfish Immunol. 2019 Nov;94:434-446. |
