For research use only. Not for therapeutic Use.
Carboxyrhodamine 110-PEG4-alkyne(Cat No.:I015646)is a bioconjugate compound used in fluorescence-based assays and drug delivery systems. It consists of a carboxyrhodamine 110 dye, which provides strong fluorescence for tracking and imaging, linked to a polyethylene glycol (PEG4) chain for improved solubility and biocompatibility. The alkyne group enables further conjugation through click chemistry, allowing for precise attachment to target molecules, such as peptides or antibodies, for specific applications. This compound is used in cellular imaging, drug targeting, and biomolecule labeling, facilitating the study of molecular interactions and therapeutic delivery in biological systems.
Catalog Number | I015646 |
CAS Number | 2055103-66-5 |
Molecular Formula | C₃₂H₃₃N₃O₈ |
Purity | ≥95% |
Target | PROTAC Linkers |
IUPAC Name | 2-(3-amino-6-iminoxanthen-9-yl)-5-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethylcarbamoyl]benzoic acid |
InChI | InChI=1S/C32H33N3O8/c1-2-10-39-12-14-41-16-17-42-15-13-40-11-9-35-31(36)21-3-6-24(27(18-21)32(37)38)30-25-7-4-22(33)19-28(25)43-29-20-23(34)5-8-26(29)30/h1,3-8,18-20,33H,9-17,34H2,(H,35,36)(H,37,38) |
InChIKey | JXQJIYQBZLRJHC-UHFFFAOYSA-N |
SMILES | C#CCOCCOCCOCCOCCNC(=O)C1=CC(=C(C=C1)C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N)C(=O)O |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |