For research use only. Not for therapeutic Use.
Carboxyrhodamine 110-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].<br>PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Catalog Number | I015646 |
| CAS Number | 2055103-66-5 |
| Molecular Formula | C₃₂H₃₃N₃O₈ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
