For research use only. Not for therapeutic Use.
Cariprazine-d8(CAT: C000090) is a deuterated cyclohexyl urea modulator of D2 receptors and/or modulators of D3 receptors for disease treatment in relation to increased enzymic metabolic stability. Also, it is derived from N-(2,3-Dichlorophenyl)piperazine-d8, which is a compound useful in organic synthesis. A deuterated form of Cariprazine, which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania, and depression.
| Catalog Number | C000090 |
| CAS Number | 1308278-69-4 |
| Synonyms | N’-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl-2,2-d2]cyclohexyl]-N,N-di(methyl-d3)-urea; |
| Molecular Formula | C₂₁H₂₄D₈Cl₂N₄O |
| Purity | ≥95% |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Off-White to Pale Beige Solid |
| Storage | -20°C, Inert atmosphere |
| Reference | Newbold, R., et al.: PCT Int. Appl. (2011), WO 2011060363 A2 |
