For research use only. Not for therapeutic Use.
Carmoterol, also known as CHF-4226 and TA-2005, is a long-acting, and selective beta 2-adrenoceptor agonist. TA-2005 exerts potent bronchodilating effects with a long duration of action in vivo, and its potency ratios to the other reference drugs were gre
| Catalog Number | I004575 |
| CAS Number | 137888-11-0 (HCl) |
| Synonyms | TA-2005; TA 2005; TA2005. CHF 4226.01; CHF-4226.; CHF4226.; TA-2005 hydrochloride; Carmoterol HCl; Carmoterol hydrochloride;8-Hydroxy-5-(1-hydroxy-2-(N-(2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)carbostyril hydrochloride |
| Molecular Formula | C21H25ClN2O4 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| IUPAC Name | 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]-1H-quinolin-2-one;hydrochloride |
| InChI | InChI=1S/C21H24N2O4.ClH/c1-13(11-14-3-5-15(27-2)6-4-14)22-12-19(25)16-7-9-18(24)21-17(16)8-10-20(26)23-21;/h3-10,13,19,22,24-25H,11-12H2,1-2H3,(H,23,26);1H/t13-,19+;/m1./s1 |
| InChIKey | SYCWERNQGSKYAG-QVRIGTRMSA-N |
| SMILES | CC(CC1=CC=C(C=C1)OC)NCC(C2=C3C=CC(=O)NC3=C(C=C2)O)O.Cl |
| Reference | </br> 1: Rossoni G, Manfredi B, Razzetti R, Civelli M, Berti F. Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs. Pulm Pharmacol Ther. 2007;20 |
