Carumonam Sodium

• CAT Number: I005665
• CAS Number: 86832-68-0
• Molecular Formula: C12H12N6Na2O10S2
• Molecular Weight: 510.36
• Purity: ≥95%
• Synonyms: Carumonam Sodium; AMA-1080; Ro-17-2301; AMA 1080; Ro 17 2301; AMA1080; Ro172301; Amasulin;sodium 2-(((1-(2-aminothiazol-4-yl)-2-(((2S,3S)-2-((carbamoyloxy)methyl)-4-oxo-1-sulfonatoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)acetate
• Target: Antibiotic
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: disodium;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfonatoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyacetate
• InChI: InChI=1S/C12H14N6O10S2.2Na/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5(1-27-12(14)23)18(10(8)22)30(24,25)26;;/h3,5,8H,1-2H2,(H2,13,15)(H2,14,23)(H,16,21)(H,19,20)(H,24,25,26);;/q;2*+1/p-2/b17-7+;;/t5-,8+;;/m1../s1
• InChIKey: BGGXRVPCJUKHTQ-REOVRMSNSA-L
• SMILES: O=S(N1[C@H](COC(N)=O)[C@H](NC(C(C2=CSC(N)=N2)=NOCC([O-])=O)=O)C1=O)([O-])=O.[Na+].[Na+]

Carumonam Sodium(CAT: I005665) is a monobactam antibiotic with potent activity against Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas aeruginosa. It acts by inhibiting bacterial cell wall synthesis through selective binding to penicillin-binding proteins (PBPs), leading to bacterial lysis. Carumonam Sodium is stable against most β-lactamases, making it effective in treating infections caused by β-lactamase-producing bacteria. Its applications include research on antibiotic resistance mechanisms, β-lactam pharmacodynamics, and the development of therapies for multidrug-resistant bacterial infections. Its high specificity and efficacy make it a valuable tool for studying Gram-negative bacterial pathogenesis and antibiotic efficacy.