Carvedilol

• CAT Number: A000894
• CAS Number: 72956-09-3
• Molecular Formula: C24H26N2O4
• Molecular Weight: 406.50
• Purity: ≥95%
• Synonyms: 72956-09-3; Coreg; Dilatrend; Carvedilolum; Eucardic
• Target: Neuronal Signaling
• Solubility: >20.3mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
• InChI: InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
• InChIKey: OGHNVEJMJSYVRP-UHFFFAOYSA-N
• SMILES: COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O

Carvedilol（Cat No.:A000894）is a non-selective beta-blocker with alpha-1 adrenergic blocking activity, primarily used to manage heart failure, hypertension, and left ventricular dysfunction following myocardial infarction. It reduces heart rate and myocardial contractility, improving cardiac output and overall heart function. Additionally, carvedilol exhibits antioxidant properties, which may contribute to its cardioprotective effects. The drug enhances exercise tolerance and reduces hospitalizations in heart failure patients. With a favorable safety profile, common side effects include dizziness, fatigue, and hypotension. Carvedilol is an essential component of heart failure management and a valuable therapeutic option for cardiovascular health.

Reference

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