Carvedilol metabolite 4-Hydroxyphenyl Carvedilol

• CAT Number: I001631
• CAS Number: 142227-49-4
• Molecular Formula: C24H26N2O5
• Molecular Weight: 422.47
• Purity: ≥95%
• Target: Drug Metabolite
• Solubility: 10 mM in DMSO
• Storage: 3 years -20°C powder
• IUPAC Name: 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol
• InChI: InChI=1S/C24H26N2O5/c1-29-23-13-16(27)9-10-21(23)30-12-11-25-14-17(28)15-31-22-8-4-7-20-24(22)18-5-2-3-6-19(18)26-20/h2-10,13,17,25-28H,11-12,14-15H2,1H3
• InChIKey: ZCJHEORDHXCJNB-UHFFFAOYSA-N
• SMILES: COC1=C(C=CC(=C1)O)OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O

4-Hydroxyphenyl Carvedilol(CAT: I001631) is a primary metabolite of Carvedilol, a non-selective beta-adrenergic blocker with additional alpha-1 blocking and antioxidant properties. This metabolite retains pharmacological activity, contributing to the drug’s overall cardiovascular effects, including vasodilation and cardioprotection. It is particularly valuable in cardiovascular research, aiding in the study of beta-blocker metabolism, pharmacokinetics, and pharmacodynamics. 4-Hydroxyphenyl Carvedilol serves as a critical tool for investigating the metabolic pathways of Carvedilol and exploring its therapeutic implications in heart failure and hypertension management.