CASP3 Activator 1541

• CAT Number: I024144
• CAS Number: 1100353-03-4
• Molecular Formula: C24H17N3O4
• Molecular Weight: 411.42
• Purity: 98%
• Synonyms: CASP3 Activator-1541; CASP3-Activator 1541; CASP3-Activator-1541; CASP3 Activator 1541
• Target: Caspase
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: N-(3-(Imidazo[1,2-a]pyridin-2-yl)phenyl)-8-methoxy-2-oxo-2H-chromene-3-carboxamide
• InChI: InChI=1S/C24H17N3O4/c1-30-20-9-5-7-16-13-18(24(29)31-22(16)20)23(28)25-17-8-4-6-15(12-17)19-14-27-11-3-2-10-21(27)26-19/h2-14H,1H3,(H,25,28)
• InChIKey: PQLVYQVWNPGJML-UHFFFAOYSA-N
• SMILES: O=C(C(C1=O)=CC2=C(O1)C(OC)=CC=C2)NC3=CC=CC(C4=CN5C=CC=CC5=N4)=C3

CASP3 Activator 1541(CAT: I024144) is a small molecule activator of caspase-3, an enzyme that plays a critical role in programmed cell death (apoptosis). Activation of caspase-3 is an important step in the execution of the apoptotic process, and dysregulation of caspase-3 activity has been implicated in various diseases, including cancer and neurodegenerative disorders. CASP3 Activator 1541 works by binding to the active site of caspase-3 and inducing its activation, leading to the initiation of apoptosis in target cells. CASP3 Activator 1541 has shown promising results in preclinical studies, particularly in the treatment of cancer. It has been found to be effective in inducing apoptosis in cancer cells and sensitizing them to other types of therapies, such as chemotherapy and radiation therapy.