Caspase-3-IN-1

For research use only. Not for therapeutic Use.

  • CAT Number: I043581
  • CAS Number: 872254-32-5
  • Molecular Formula: C26H25N3O6S
  • Molecular Weight: 507.56
  • Purity: ≥95%
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Caspase-3-IN-1(Cat No.:I043581)is a selective inhibitor of caspase-3, a key enzyme involved in the execution phase of apoptosis (programmed cell death). Caspase-3 is crucial for the cleavage of various cellular substrates, leading to the dismantling of the cell. By inhibiting caspase-3, Caspase-3-IN-1 helps to prevent unwanted cell death, making it a valuable tool in research related to neurodegenerative diseases, cardiovascular conditions, and cancer, where controlling apoptosis may be beneficial. It has potential therapeutic applications for protecting healthy cells in conditions where apoptosis is dysregulated, offering insight into cellular survival mechanisms.


CAS Number 872254-32-5
Synonyms

1-[(4-methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione

Molecular Formula C26H25N3O6S
Purity ≥95%
IUPAC Name 1-[(4-methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione
InChI InChI=1S/C26H25N3O6S/c1-34-20-8-6-18(7-9-20)16-28-24-11-10-22(14-23(24)25(30)26(28)31)36(32,33)29-13-3-4-19(29)17-35-21-5-2-12-27-15-21/h2,5-12,14-15,19H,3-4,13,16-17H2,1H3/t19-/m0/s1
InChIKey XDHJBIYJRNFDKS-IBGZPJMESA-N
SMILES COC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CCC[C@H]4COC5=CN=CC=C5)C(=O)C2=O
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