For research use only. Not for therapeutic Use.
Catechin is a polyphenolic flavonoid which has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-<wbr></wbr>tocopherol in certain <em>in vitro</em> assays of lipid peroxidation. Catechin inhibits the free radical-<wbr></wbr>induced oxidation of isolated LDL by AAPH. It has also been reported to act as an inhibitor of COX-<wbr></wbr>1 with an IC<sub>50</sub> of about 80 µM. Catechin and other related procyanidin compounds have antitumor activity when tested in a two-<wbr></wbr>stage mouse epidermal carcinoma model employing topical application.
| Catalog Number | R067355 |
| CAS Number | 225937-10-0 |
| Synonyms | D-(+)-Catechin;Catechuic Acid;Cyanidol |
| Molecular Formula | C15H14O6 · XH2O |
| Purity | ≥95% |
| Target | COX |
| Storage | 4°C |
| InChI | InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1 |
| InChIKey | OFUMQWOJBVNKLR-NQQJLSKUSA-N |
| SMILES | OC1=CC([C@@H](O2)[C@@H](O)CC3=C2C=C(O)C=C3O)=CC=C1O.O |
| Reference | 1.Zhao, J.,Wang, J.,Chen, Y., et al. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3/’-gallate as the most effective antioxi |
