For research use only. Not for therapeutic Use.
CAY10590 (GK115) is an inhibitor of secreted phospholipase A2 (sPLA2) and can be used for the research of chronic inflammatory kidney diseases[1].
CAY10590 (GK115) (0-10 μM; 24 h) inhibits IL-1β/forskolin-stimulated PGE2 formation in mesangial cells[1].
| Catalog Number | R064359 |
| CAS Number | 1101136-50-8 |
| Synonyms | (4R)-4-(7-phenylheptanoylamino)octanoic acid |
| Molecular Formula | C21H33NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H33NO3/c1-2-3-14-19(16-17-21(24)25)22-20(23)15-10-5-4-7-11-18-12-8-6-9-13-18/h6,8-9,12-13,19H,2-5,7,10-11,14-17H2,1H3,(H,22,23)(H,24,25)/t19-/m1/s1 |
| InChIKey | ANTPELWBOPVWPH-LJQANCHMSA-N |
| SMILES | CCCCC(CCC(=O)O)NC(=O)CCCCCCC1=CC=CC=C1 |
| Reference | [1]. Vasilakaki S, et al. Small Peptides Able to Suppress Prostaglandin E₂ Generation in Renal Mesangial Cells. Molecules. 2018 Jan 13;23(1):158. |
