For research use only. Not for therapeutic Use.
CB-13 (Cat.No:I005707), also known as SAB-378, CRB-13, is a potent, orally active CB1/CB2 receptor agonist with limited brain penetration (EC50 values are 6.1 and 27.9 nM for CB1 and CB2 receptors respectively). It displays antihyperalgesic activity in a rat model of neuropathic pain with no CNS side effects.
| Catalog Number | I005707 |
| CAS Number | 432047-72-8 |
| Synonyms | CB-13; CB 13; CB13; CRA-13; CRA 13; CRA13; USAB-378; SAB 378; SAB378.;1-Naphthalenyl(4-(pentyloxy)-1-naphthalenyl)methanone |
| Molecular Formula | C26H24O2 |
| Purity | ≥95% |
| Target | Cannabinoid Agonist |
| Solubility | Soluble in DMSO, not in water |
| Storage | Store at -20°C |
| IUPAC Name | naphthalen-1-yl-(4-pentoxynaphthalen-1-yl)methanone |
| InChI | InChI=1S/C26H24O2/c1-2-3-8-18-28-25-17-16-24(21-13-6-7-14-22(21)25)26(27)23-15-9-11-19-10-4-5-12-20(19)23/h4-7,9-17H,2-3,8,18H2,1H3 |
| InChIKey | RSUMDJRTAFBISX-UHFFFAOYSA-N |
| SMILES | CCCCCOC1=CC=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43 |
| Reference | </br>1:Uchiyama N, Kikura-Hanajiri R, Hakamatsuka T. [Evaluation of an on-site drug-testing device for the detection of synthetic cannabinoids in illegal herbal products].</br> Yakugaku Zasshi. 2015;135(3):535-41. doi: 10.1248/yakushi.14-00247. Epub 2015 Jan 19. Japanese. PubMed PMID: 25759062. |
