For research use only. Not for therapeutic Use.
Cbl-b-IN-5 (compound 6) is a Cbl-b inhibitor (IC50=3-10 µM). Cbl-b-IN-5 has the potential to be used in the study of cancer and related diseases amenable to immune system modulation[1].
| Catalog Number | I040888 |
| CAS Number | 2368835-59-8 |
| Synonyms | N-[3-[1-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]phenyl]pyridine-2-carboxamide |
| Molecular Formula | C17H17N5OS |
| Purity | ≥95% |
| InChI | InChI=1S/C17H17N5OS/c1-12(24-17-21-19-11-22(17)2)13-6-5-7-14(10-13)20-16(23)15-8-3-4-9-18-15/h3-12H,1-2H3,(H,20,23) |
| InChIKey | BOVJKQTZTZBOBN-UHFFFAOYSA-N |
| SMILES | CC(C1=CC(=CC=C1)NC(=O)C2=CC=CC=N2)SC3=NN=CN3C |
| Reference | [1]. Paul A. Barsanti, et al. Inhibitors of cbl-b and methods of use thereof. Patent WO2019148005A1. |
