For research use only. Not for therapeutic Use.
CBP/p300-IN-1 is a CBP/EP300 bromodomain inhibitor.
| Catalog Number | I019524 |
| CAS Number | 2443789-32-8 |
| Synonyms | tert-butyl 3-[(1-acetyl-5-methoxyindole-3-carbonyl)amino]-4-fluorobenzoate |
| Molecular Formula | C23H23FN2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H23FN2O5/c1-13(27)26-12-17(16-11-15(30-5)7-9-20(16)26)21(28)25-19-10-14(6-8-18(19)24)22(29)31-23(2,3)4/h6-12H,1-5H3,(H,25,28) |
| InChIKey | BNTANBUTBDVIHY-UHFFFAOYSA-N |
| SMILES | CC(=O)N1C=C(C2=C1C=CC(=C2)OC)C(=O)NC3=C(C=CC(=C3)C(=O)OC(C)(C)C)F |
| Reference | [1]. Xiang Q, et al. Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer. Eur J Med Chem. 2018 Mar 10;147:238-252. |
