For research use only. Not for therapeutic Use.
Cbz-Ala-Ala-Asn TFA is a peptide that designed based on the sequence of the substrate of legumain. Legumain is a cysteine protease. Cbz-Ala-Ala-Asn TFA can be applied as a scaffold for drug delivery[1][2].
| Catalog Number | I041410 |
| Synonyms | (2S)-4-amino-4-oxo-2-[[(2S)-2-[[(2S)-2-(phenylmethoxycarbonylamino)propanoyl]amino]propanoyl]amino]butanoic acid;2,2,2-trifluoroacetic acid |
| Molecular Formula | C20H25F3N4O9 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H24N4O7.C2HF3O2/c1-10(16(25)22-13(17(26)27)8-14(19)23)20-15(24)11(2)21-18(28)29-9-12-6-4-3-5-7-12;3-2(4,5)1(6)7/h3-7,10-11,13H,8-9H2,1-2H3,(H2,19,23)(H,20,24)(H,21,28)(H,22,25)(H,26,27);(H,6,7)/t10-,11-,13-;/m0./s1 |
| InChIKey | XHTNNYYTYDZFEL-SQRKDXEHSA-N |
| SMILES | CC(C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(C)NC(=O)OCC1=CC=CC=C1.C(=O)(C(F)(F)F)O |
| Reference | [1]. Shan L. Cy5-labeled aza-peptidyl Pro-Asn epoxide. 2010 May 12 [updated 2010 Jun 3]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. [2]. Poreba M. Recent advances in the development of legumain-selective chemical probes and peptide prodrugs. Biol Chem. 2019 Nov 26;400(12):1529-1550. |
