Cbz-NH-PEG1-CH2COOH

• CAT Number: I016184
• CAS Number: 1260092-43-0
• Molecular Formula: C₁₂H₁₅NO₅
• Molecular Weight: 253.25
• Purity: ≥95%
• Target: PROTAC Linkers
• IUPAC Name: 2-[2-(phenylmethoxycarbonylamino)ethoxy]acetic acid
• InChI: InChI=1S/C12H15NO5/c14-11(15)9-17-7-6-13-12(16)18-8-10-4-2-1-3-5-10/h1-5H,6-9H2,(H,13,16)(H,14,15)
• InChIKey: MBFFUILDSABICM-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)COC(=O)NCCOCC(=O)O

Cbz-NH-PEG1-CH2COOH（Cat No.:I016184）is a compound consisting of a carbobenzyloxy (Cbz) protecting group, a polyethylene glycol (PEG) chain with a single ethylene glycol unit (PEG1), and a carboxylic acid group (CH2COOH). The Cbz group is often used to protect amines during synthesis, while PEG1 enhances solubility and bioavailability, making this compound useful in drug design and delivery systems. The carboxyl group provides potential for conjugation or further chemical modification. This structure is often used in peptide synthesis, drug formulation, and the development of targeted therapies for various biomedical applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.