Cbz-NH-PEG2-C2-acid

• CAT Number: I015962
• CAS Number: 1347750-76-8
• Molecular Formula: C₁₅H₂₁NO₆
• Molecular Weight: 311.33
• Purity: ≥95%
• Target: PROTAC Linkers
• IUPAC Name: 3-[2-[2-(phenylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C15H21NO6/c17-14(18)6-8-20-10-11-21-9-7-16-15(19)22-12-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,16,19)(H,17,18)
• InChIKey: XOMNIRHPTPYIMF-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)COC(=O)NCCOCCOCCC(=O)O

Cbz-NH-PEG2-C2-acid（Cat No.:I015962）is a compound that combines a carbobenzyloxy (Cbz) group, polyethylene glycol (PEG) chain, and a carboxylic acid (C2-acid) functional group. The Cbz group serves as a protecting group for amino acids or peptides, commonly used in peptide synthesis to prevent unwanted reactions. The PEG2 linker, a two-unit polyethylene glycol chain, provides water solubility and stability, facilitating better bioavailability and drug delivery. This compound is often utilized in the development of drug conjugates or targeted therapies, enhancing the pharmacokinetic properties of peptides or other bioactive molecules in research or therapeutic applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562