CCT365623 (hydrochloride)

• CAT Number: I005989
• CAS Number: 2126136-98-7
• PubChem Substance ID: 139266765
• Molecular Formula: C18H18ClNO4S3
• Molecular Weight: 444.00
• Purity: ≥95%
• IUPAC Name: [5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine;hydrochloride
• InChI: InChI=1S/C18H17NO4S3.ClH/c1-25(20,21)16-9-14(13-5-3-2-4-6-13)10-17(11-16)26(22,23)18-8-7-15(12-19)24-18;/h2-11H,12,19H2,1H3;1H
• InChIKey: MKBRQENFVVWIGU-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)C1=CC(=CC(=C1)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(S3)CN.Cl

CCT365623 hydrochloride(Cat No.:I005989) is a selective and potent inhibitor of the transcription factor STAT5 (signal transducer and activator of transcription 5) pathway, which is involved in regulating various cellular processes such as cell proliferation, differentiation, and survival. It works by preventing the binding of STAT5 to its target DNA sequences, thereby inhibiting the transcription of STAT5-regulated genes. CCT365623 hydrochloride has been shown to have antiproliferative effects on a variety of cancer cells, particularly those that are dependent on STAT5 for their survival and growth, including certain types of leukemia, breast cancer, and prostate cancer. In addition to its potential as a cancer therapy, CCT365623 hydrochloride has also been studied for its potential use in treating autoimmune disorders, such as rheumatoid arthritis.