For research use only. Not for therapeutic Use.
CCT373566（Cat No.:I043563）is a selective small molecule inhibitor that targets the protein kinase AKT, which is involved in regulating cell growth, survival, and metabolism. AKT is frequently dysregulated in various cancers, contributing to tumor progression and resistance to therapy. By inhibiting AKT, CCT373566 aims to block key signaling pathways that drive cancer cell proliferation and survival, making it a promising candidate for cancer treatment. It has demonstrated potential in preclinical studies to enhance the efficacy of other cancer therapies, offering a targeted approach to treat cancers driven by AKT activation.
| CAS Number | 2378853-66-6 |
| Synonyms | (2S)-10-[[5-chloro-2-[(3R,5S)-3-hydroxy-5-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-2-cyclopropyl-3,3-difluoro-7-methyl-2,4-dihydro-1H-[1,4]oxazepino[2,3-c]quinolin-6-one |
| Molecular Formula | C26H29ClF2N6O3 |
| Purity | ≥95% |
| IUPAC Name | (2S)-10-[[5-chloro-2-[(3R,5S)-3-hydroxy-5-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-2-cyclopropyl-3,3-difluoro-7-methyl-2,4-dihydro-1H-[1,4]oxazepino[2,3-c]quinolin-6-one |
| InChI | InChI=1S/C26H29ClF2N6O3/c1-13-7-16(36)11-35(10-13)25-30-9-18(27)23(33-25)31-15-5-6-19-17(8-15)20-21(24(37)34(19)2)38-12-26(28,29)22(32-20)14-3-4-14/h5-6,8-9,13-14,16,22,32,36H,3-4,7,10-12H2,1-2H3,(H,30,31,33)/t13-,16+,22-/m0/s1 |
| InChIKey | GSGDUDAFETZSPM-IATAILRESA-N |
| SMILES | C[C@H]1C[C@H](CN(C1)C2=NC=C(C(=N2)NC3=CC4=C(C=C3)N(C(=O)C5=C4N[C@H](C(CO5)(F)F)C6CC6)C)Cl)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
