For research use only. Not for therapeutic Use.
CCX-777（Cat No.:I024264）is a selective antagonist of the chemokine receptor CCR9, which plays a crucial role in immune cell trafficking, particularly in inflammatory diseases. By blocking CCR9, CCX-777 prevents the migration of immune cells to sites of inflammation, making it a promising therapeutic agent for conditions like inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. Its targeted mechanism of action offers the potential to reduce inflammation and tissue damage without broadly suppressing the immune system, providing a more precise approach to managing chronic inflammatory conditions.
| CAS Number | 1226686-36-7 |
| Synonyms | 3-[4-(7-methoxyquinolin-8-yl)-1,4-diazepan-1-yl]-3-(2-morpholin-4-yl-1,3-thiazol-4-yl)-N-(2-pyrrolidin-1-ylethyl)propanamide |
| Molecular Formula | C31H43N7O3S |
| Purity | ≥95% |
| IUPAC Name | 3-[4-(7-methoxyquinolin-8-yl)-1,4-diazepan-1-yl]-3-(2-morpholin-4-yl-1,3-thiazol-4-yl)-N-(2-pyrrolidin-1-ylethyl)propanamide |
| InChI | InChI=1S/C31H43N7O3S/c1-40-27-8-7-24-6-4-9-33-29(24)30(27)37-14-5-13-36(16-17-37)26(22-28(39)32-10-15-35-11-2-3-12-35)25-23-42-31(34-25)38-18-20-41-21-19-38/h4,6-9,23,26H,2-3,5,10-22H2,1H3,(H,32,39) |
| InChIKey | PUPJAMOHYJWOKK-UHFFFAOYSA-N |
| SMILES | COC1=C(C2=C(C=CC=N2)C=C1)N3CCCN(CC3)C(CC(=O)NCCN4CCCC4)C5=CSC(=N5)N6CCOCC6 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
