For research use only. Not for therapeutic Use.
CD2314 is a potent and selective RARβ receptor agonist with a Kd of 195 nM in S91 melanoma cells[1].
Catalog Number | I005906 |
CAS Number | 170355-37-0 |
Synonyms | 5-(5,5,8,8-tetramethyl-6,7-dihydroanthracen-2-yl)thiophene-3-carboxylic acid |
Molecular Formula | C23H24O2S |
Purity | ≥95% |
InChI | InChI=1S/C23H24O2S/c1-22(2)7-8-23(3,4)19-11-16-9-15(6-5-14(16)10-18(19)22)20-12-17(13-26-20)21(24)25/h5-6,9-13H,7-8H2,1-4H3,(H,24,25) |
InChIKey | URUSABQSUCBGGJ-UHFFFAOYSA-N |
SMILES | CC1(CCC(C2=C1C=C3C=CC(=CC3=C2)C4=CC(=CS4)C(=O)O)(C)C)C |
Reference | [1]. Spanjaard RA, et al. Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RARgamma in induction of differentiation and apoptosis of S91 melanoma cells. J Biol Chem. 1997 Jul 25;272(30):18990-9. |