CD73-IN-1

• CAT Number: I020459
• CAS Number: 2132396-40-6
• Molecular Formula: C18H17N3O4S
• Molecular Weight: 371.41
• Purity: ≥95%
• Synonyms: 5-[(2-cyclopropyl-1H-indol-6-yl)sulfamoyl]-2-hydroxybenzamide
• InChI: InChI=1S/C18H17N3O4S/c19-18(23)14-9-13(5-6-17(14)22)26(24,25)21-12-4-3-11-7-15(10-1-2-10)20-16(11)8-12/h3-10,20-22H,1-2H2,(H2,19,23)
• InChIKey: YUGALILHRFUCAY-UHFFFAOYSA-N
• SMILES: C1CC1C2=CC3=C(N2)C=C(C=C3)NS(=O)(=O)C4=CC(=C(C=C4)O)C(=O)N

CD73-IN-1 is an inhibitor of CD73 which can be used in the treatment of cancer extracted from patent WO 2017153952 A1, example 80.

Reference

[1]. Jerry Leroy Adams, et al. 5-sulfamoyl-2-hydroxybenzamide derivatives. WO 2017153952 A1.