CDK2-IN-3

• CAT Number: R021935
• CAS Number: 222035-13-4
• Molecular Formula: C14H11BrN4O3S
• Molecular Weight: 395.23
• Purity: ≥95%
• Synonyms: 4-[(5-bromo-2-hydroxy-1H-indol-3-yl)diazenyl]benzenesulfonamide
• InChI: InChI=1S/C14H11BrN4O3S/c15-8-1-6-12-11(7-8)13(14(20)17-12)19-18-9-2-4-10(5-3-9)23(16,21)22/h1-7,17,20H,(H2,16,21,22)
• InChIKey: IWDDMLCHUYBHHD-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1N=NC2=C(NC3=C2C=C(C=C3)Br)O)S(=O)(=O)N

CDK2-IN-3 (compound 3) is a potent and selective CDK2 inhibitor with an 50 of 60 nM[1].

Reference

[1]. S T Davis, et al. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science. 2001 Jan 5;291(5501):134-7.
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