Cdk5 Substrate

• CAT Number: R065564
• CAS Number: 164669-07-2
• Molecular Formula: C53H99N15O12
• Molecular Weight: 1138.45
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]hexanoyl]amino]propanoyl]amino]hexanoyl]amino]hexanoyl]amino]-4-methylpentanoic acid
• InChI: InChI=1S/C53H99N15O12/c1-32(2)31-41(53(79)80)66-49(75)38(19-7-12-26-56)64-47(73)37(18-6-11-25-55)61-44(70)33(3)60-46(72)36(17-5-10-24-54)63-48(74)39(20-8-13-27-57)65-51(77)42-23-16-30-68(42)52(78)43(34(4)69)67-50(76)40(21-9-14-28-58)62-45(71)35-22-15-29-59-35/h32-43,59,69H,5-31,54-58H2,1-4H3,(H,60,72)(H,61,70)(H,62,71)(H,63,74)(H,64,73)(H,65,77)(H,66,75)(H,67,76)(H,79,80)/t33-,34+,35-,36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
• InChIKey: ZSZMVAFYNVHXHA-BJSZDZKQSA-N
• SMILES: CC(C)CC(C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C2CCCN2

Cdk5 Substrate(CAT: R065564) is a synthetic peptide designed for the specific detection and study of cyclin-dependent kinase 5 (Cdk5) activity. Cdk5 is a proline-directed serine/threonine kinase primarily active in neuronal tissues, where it regulates critical processes such as neuronal migration, synaptic function, and neurodegeneration. This peptide substrate contains the optimal phosphorylation sequence recognized by Cdk5, making it ideal for in vitro kinase assays, inhibitor screening, and signal transduction studies. Supplied in high purity, the Cdk5 Substrate is a valuable tool for investigating Cdk5-related pathways in neuroscience and neurodegenerative disease research.