For research use only. Not for therapeutic Use.
CDK7-IN-21 (compound A22) is a potent CDK7 inhibitor[1].
| Catalog Number | I041168 |
| CAS Number | 2766124-39-2 |
| Synonyms | 2-fluoro-N-[1-[2-[[[2-[[(3R,4R)-3-hydroxypiperidin-4-yl]methylamino]-8-propan-2-ylpyrazolo[1,5-a][1,3,5]triazin-4-yl]amino]methyl]phenyl]isoquinolin-6-yl]prop-2-enamide |
| Molecular Formula | C33H36FN9O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C33H36FN9O2/c1-19(2)27-17-39-43-30(27)41-32(37-16-23-10-12-35-18-28(23)44)42-33(43)38-15-22-6-4-5-7-25(22)29-26-9-8-24(40-31(45)20(3)34)14-21(26)11-13-36-29/h4-9,11,13-14,17,19,23,28,35,44H,3,10,12,15-16,18H2,1-2H3,(H,40,45)(H2,37,38,41,42)/t23-,28+/m1/s1 |
| InChIKey | PDKSTEKFCWNJFC-LXFBAYGMSA-N |
| SMILES | CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=CC=C3C4=NC=CC5=C4C=CC(=C5)NC(=O)C(=C)F)NCC6CCNCC6O |
| Reference | [1]. Kiyean NAM, et al. Compounds for degradation of cyclin-dependent kinase 7 (cdk7). Patent. WO2022248682A1. |
