For research use only. Not for therapeutic Use.
Cefadroxil-d4 hydrate (CAS: 1426174-38-0), a premium pharmaceutical research compound designed for advanced antibacterial studies. As a deuterated analog of Cefadroxil, it offers enhanced stability and improved pharmacokinetic properties. Cefadroxil-d4 hydrate is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel antibacterial therapies. Trusted by leading laboratories, Cefadroxil-d4 hydrate is your go-to solution for cutting-edge antibacterial research. Unlock new possibilities in infection treatment with Cefadroxil-d4 hydrate, where innovation meets reliability.
| Catalog Number | S000262 |
| CAS Number | 1426174-38-0 |
| Molecular Formula | C16H15D4N3O6S |
| Purity | ≥95% |
| IUPAC Name | (6R,7R)-7-[[(2R)-2-amino-2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate |
| InChI | InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1/i2D,3D,4D,5D; |
| InChIKey | NBFNMSULHIODTC-AUTKPGNWSA-N |
| SMILES | [2H]C1=C(C(=C(C(=C1[C@H](C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(=O)O)N)[2H])[2H])O)[2H].O |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Chen X, et al. Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study. Biochem Pharmacol. 2017 May 1;131:89-97. [3]. Hu Y, et al. Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice. Biochem Pharmacol. 2016 May 1;107:81-90. |
