For research use only. Not for therapeutic Use.
Cefcapene Pivoxil Hydrochloride（Cat No.:I005921）is an oral third-generation cephalosporin antibiotic used to treat various bacterial infections, including respiratory, urinary, and skin infections. It is a prodrug, which, upon absorption, converts into its active form, cefcapene, enabling effective bacterial cell wall synthesis inhibition. This action targets gram-positive and gram-negative bacteria, making it useful against a broad spectrum of pathogens. With high bioavailability and a favorable safety profile, Cefcapene Pivoxil Hydrochloride is valuable in outpatient treatment settings. Its efficacy and low resistance risk make it an essential choice in modern antimicrobial therapy.
| Catalog Number | I005921 |
| CAS Number | 147816-24-8(HCl) |
| Synonyms | Cefcapene Pivoxil Hydrochloride; S-1108; S 1108; S1108; Flomox; Flumax;(pivaloyloxy)methyl (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)pent-2-enamido)-3-((carbamoyloxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride |
| Molecular Formula | C23H30ClN5O8S2 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| IUPAC Name | 2,2-dimethylpropanoyloxymethyl (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydrate;hydrochloride |
| InChI | InChI=1S/C23H29N5O8S2.ClH.H2O/c1-5-6-12(13-9-38-21(24)26-13)16(29)27-14-17(30)28-15(11(7-34-22(25)33)8-37-18(14)28)19(31)35-10-36-20(32)23(2,3)4;;/h6,9,14,18H,5,7-8,10H2,1-4H3,(H2,24,26)(H2,25,33)(H,27,29);1H;1H2/b12-6-;;/t14-,18-;;/m1../s1 |
| InChIKey | LUXIJPQYUCFVAL-XRLCNELCSA-N |
| SMILES | CC/C=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)OCOC(=O)C(C)(C)C.O.Cl |
| Reference | </br>1:Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis. Murakami M, Masuda K, Utsunomiya R, Oda F, Namba C, Sayama K.Dermatology. 2015;231(4):304-11. doi: 10.1159/000439401. Epub 2015 Oct 7. PMID: 26440444 </br>2:Positive skin prick test to cefcapene pivoxil hydrochloride hydrate: a case report. Yamazato S, Nakai N, Katoh N.Allergol Int. 2013 Jun;62(2):263-4. doi: 10.2332/allergolint.12-LE-0524. Epub 2013 Apr 25. No abstract available. PMID: 23612491 Free Article</br>3:Drug eruption induced by cefcapene pivoxil hydrochloride. Kawada A, Aragane Y, Maeda A, Asai M, Shiraishi H, Tezuka T.Contact Dermatitis. 2001 Mar;44(3):197. No abstract available. PMID: 11218007 |
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