Cefetamet pivoxil hydrochloride

• CAT Number: I000455
• CAS Number: 111696-23-2
• Molecular Formula: C20H26ClN5O7S2
• Molecular Weight: 548.03
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• IUPAC Name: 2,2-dimethylpropanoyloxymethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydrochloride
• InChI: InChI=1S/C20H25N5O7S2.ClH/c1-9-6-33-16-12(23-14(26)11(24-30-5)10-7-34-19(21)22-10)15(27)25(16)13(9)17(28)31-8-32-18(29)20(2,3)4;/h7,12,16H,6,8H2,1-5H3,(H2,21,22)(H,23,26);1H/b24-11-;/t12-,16-;/m1./s1
• InChIKey: XAAOHMIKXULDKJ-IZXJIOGHSA-N
• SMILES: CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)OCOC(=O)C(C)(C)C.Cl

Cefetamet pivoxil hydrochloride（Cat No.:I000455）is an oral prodrug of cefetamet, a third-generation cephalosporin antibiotic with broad-spectrum activity against gram-positive and gram-negative bacteria. Once ingested, it converts to its active form, cefetamet, which inhibits bacterial cell wall synthesis, leading to cell lysis and bacterial death. It is particularly effective in treating respiratory and urinary tract infections. Cefetamet pivoxil hydrochloride’s oral bioavailability makes it convenient for outpatient therapy, and its efficacy against common pathogens has made it valuable in clinical settings for managing bacterial infections.

Reference

[1]. Sateesha S, et al. Formulation development and rheological studies of palatable cefetamet pivoxil hydrochloride dry powdersuspension. Daru. 2011;19(2):118-125.