Cefminox sodium

• CAT Number: R004253
• CAS Number: 92636-39-0
• Molecular Formula: C16H20N7NaO7S3
• Molecular Weight: 541.56
• Purity: ≥95%
• Target: Antibiotic
• Storage: -20°C
• IUPAC Name: sodium;(6R,7S)-7-[[2-[(2S)-2-amino-2-carboxyethyl]sulfanylacetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• InChI: InChI=1S/C16H21N7O7S3.Na/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26;/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28);/q;+1/p-1/t8-,14-,16+;/m1./s1
• InChIKey: SBIDXLKJYJVQOE-YNJMIPHHSA-M
• SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSC[C@H](C(=O)O)N)OC)SC2)C(=O)[O-].[Na+]

Cefminox Sodium（Cat No.:R004253）is a high-purity, second-generation cephamycin antibiotic widely used in antimicrobial research. It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Known for its strong resistance to β-lactamases, Cefminox Sodium is particularly effective against resistant bacterial strains. Its stability and solubility in sodium salt form make it suitable for pharmacological and microbiological studies. This compound is essential for exploring therapeutic strategies and mechanisms to combat bacterial infections and resistance.

Reference

Georgopapadakou, N. H. /Mechanisms of Action of Cephalosporin 3/’-quinolone Esters, Carbamates, and Tertiary Amines in Escherichia Coli./ American Society for Microbiology 37.3 (1992): 559-65. Antimicrobial Agents and Chemotherapy. Web. 21 Aug. 2012.