For research use only. Not for therapeutic Use.
Cefotaxime Acid(Cat No.:I010116)is the active, non-sodium form of cefotaxime, a third-generation cephalosporin antibiotic effective against a broad spectrum of Gram-negative and some Gram-positive bacteria. It works by inhibiting bacterial cell wall synthesis, making it suitable for treating severe infections like respiratory tract infections, septicemia, and meningitis. Cefotaxime Acid is especially valued in hospital settings for its stability against certain beta-lactamases, enhancing its efficacy against resistant strains. This form is typically used in research and pharmaceutical applications to study its pharmacodynamics and antibiotic potential.
Catalog Number | I010116 |
CAS Number | 63527-52-6 |
Synonyms | Cephotaxime; RU24662; RU-24662; RU 24662; Taxim;(6R,7R)-3-(acetoxymethyl)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
Molecular Formula | C16H17N5O7S2 |
Purity | 98% |
Target | Beta-lactamase |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Store at 0-8 °C |
IUPAC Name | (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
InChI | InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1 |
InChIKey | GPRBEKHLDVQUJE-QSWIMTSFSA-N |
SMILES | O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=NOC)=O)C1=O)O |