Cefotaxime-d3

• CAT Number: R048044
• CAS Number: NA
• Molecular Formula: C₁₆H₁₄D₃N₅O₇S₂
• Molecular Weight: 458.48
• Purity: ≥95%
• Synonyms: (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxC587242yimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid-d3; Cefotax-d3; HR 756-d3; Pretor-d3; Tolycar-d3
• Storage: -20°C
• IUPAC Name: (6R,7R)-3-(acetyloxymethyl)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(trideuteriomethoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9+/t10-,14-/m1/s1/i2D3
• InChIKey: GPRBEKHLDVQUJE-CXXZQAFYSA-N
• SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O

Cefotaxime-d3（Cat No.:R048044） is a deuterated version of Cefotaxime, where three hydrogen atoms are replaced with deuterium. This isotopic modification increases the stability of the molecule, making it particularly useful for pharmacokinetic and metabolic studies. Cefotaxime is a third-generation cephalosporin antibiotic used widely to treat bacterial infections by inhibiting cell wall synthesis. The deuterated form, Cefotaxime-d3, allows for precise tracking and analysis of the antibiotic’s degradation and clearance in the body, enhancing the understanding of its pharmacodynamics and helping to optimize dosage regimens for more effective treatment outcomes and reduced resistance development.