Cefotetan

• CAT Number: R046356
• CAS Number: 69712-56-7
• Molecular Formula: C17H17N7O8S4
• Molecular Weight: 575.60
• Purity: ≥95%
• Synonyms: (6R,7S)-7-[[[4-(2-Amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Apacef
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (6R,7S)-7-[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/t13?,15-,17+/m1/s1
• InChIKey: SRZNHPXWXCNNDU-RHBCBLIFSA-N
• SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C4SC(=C(C(=O)N)C(=O)O)S4)OC)SC2)C(=O)O

Cefotetan（Cat No.:R046356）is a second-generation cephamycin antibiotic with a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, including anaerobes. It works by inhibiting bacterial cell wall synthesis, resulting in cell death. Cefotetan is commonly used for treating respiratory, urinary tract, intra-abdominal, and gynecological infections, and is particularly valued for surgical prophylaxis due to its extended half-life and effectiveness in preventing postoperative infections. It is resistant to many beta-lactamases, making it useful in infections caused by beta-lactam-resistant organisms, and is a reliable choice in hospital settings.