Cefpodoxime sodium salt

For research use only. Not for therapeutic Use.

  • CAT Number: R004785
  • CAS Number: 82619-04-3
  • Molecular Formula: C15H16N5NaO6S2
  • Molecular Weight: 449.44
  • Purity: ≥95%
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Cefpodoxime sodium salt is a third generation cephalosporin &beta;-lactam antibiotic.</br>Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. However, like many cephalosporins, cefpodoxime is stable in the presence of β-lactamases.


Catalog Number R004785
CAS Number 82619-04-3
Molecular Formula C15H16N5NaO6S2
Purity ≥95%
Storage -20°C, store protected from light.
Reference

<p>Georgopapadakou, N. H. /Mechanisms of Action of Cephalosporin 3/’-quinolone Esters, Carbamates, and Tertiary Amines in Escherichia Coli./ <em>American Society for Microbiology</em> 37.3 (1992): 559-65. <em>Antimicrobial Agents and Chemotherapy</em>. Web. 21 Aug. 2012.</p></span></p>

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