For research use only. Not for therapeutic Use.
Cefpodoxime sodium salt is a third generation cephalosporin β-lactam antibiotic.</br>Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. However, like many cephalosporins, cefpodoxime is stable in the presence of β-lactamases.
Catalog Number | R004785 |
CAS Number | 82619-04-3 |
Molecular Formula | C15H16N5NaO6S2 |
Purity | ≥95% |
Storage | -20°C, store protected from light. |
Reference | <p>Georgopapadakou, N. H. /Mechanisms of Action of Cephalosporin 3/’-quinolone Esters, Carbamates, and Tertiary Amines in Escherichia Coli./ <em>American Society for Microbiology</em> 37.3 (1992): 559-65. <em>Antimicrobial Agents and Chemotherapy</em>. Web. 21 Aug. 2012.</p></span></p> |