For research use only. Not for therapeutic Use.
Ceftazidime（Cat No.:I004702）is a third-generation cephalosporin antibiotic with broad-spectrum activity against Gram-negative bacteria, including Pseudomonas aeruginosa. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), disrupting cell wall integrity and leading to cell lysis. Ceftazidime is commonly used to treat infections such as pneumonia, urinary tract infections, and septicemia caused by susceptible organisms. It is administered intravenously or intramuscularly and is often selected for serious infections, particularly in immunocompromised patients. The drug is generally well tolerated but can cause side effects like gastrointestinal disturbances or allergic reactions.
| Catalog Number | I004702 |
| CAS Number | 72558-82-8 |
| Molecular Formula | C22H22N6O7S2 |
| Purity | ≥95% |
| Target | Antibacterial |
| Solubility | DMSO 55 mg/ml |
| Storage | Store at 4℃ |
| IUPAC Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| InChI | InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13-/t14-,18-/m1/s1 |
| InChIKey | ORFOPKXBNMVMKC-DWVKKRMSSA-N |
| SMILES | CC(C)(C(=O)O)O/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] |
| Reference | <p style=/line-height:25px/> |
