For research use only. Not for therapeutic Use.
Ceftezole Sodium（Cat No.:I018207）is a broad-spectrum cephalosporin antibiotic used in the treatment of various bacterial infections. It is effective against a wide range of Gram-positive and Gram-negative bacteria, including Staphylococcus spp., Streptococcus spp., and Escherichia coli. This second-generation cephalosporin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, disrupting the integrity of the cell wall, leading to bacterial cell lysis. Ceftezole Sodium is commonly used in hospital settings for surgical prophylaxis, respiratory tract infections, urinary tract infections, and skin and soft tissue infections.
| Catalog Number | I018207 |
| CAS Number | 41136-22-5 |
| Molecular Formula | C₁₃H₁₁N₈NaO₄S₃ |
| Purity | ≥95% |
| Target | Bacterial |
| IUPAC Name | sodium;(6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate |
| InChI | InChI=1S/C13H12N8O4S3.Na/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13;/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25);/q;+1/p-1/t8-,11-;/m1./s1 |
| InChIKey | UGUMHWUOXWFPFH-JHQAJZDGSA-M |
| SMILES | C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CN3C=NN=N3)C(=O)[O-])CSC4=NN=CS4.[Na+] |
| Reference | [1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83.<br>[2]. Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo). 1976 Oct;29(10):1071-82. |
