Ceftibuten

• CAT Number: I005714
• CAS Number: 97519-39-6
• Molecular Formula: C15H14N4O6S2
• Molecular Weight: 410.42
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• InChI: InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1
• InChIKey: UNJFKXSSGBWRBZ-BJCIPQKHSA-N
• SMILES: C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\CC(=O)O)/C3=CSC(=N3)N)C(=O)O

Ceftibuten（Cat No.:I005714）is a third-generation cephalosporin antibiotic primarily effective against Gram-negative bacteria. Administered orally, it works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Ceftibuten is commonly prescribed for respiratory tract infections, such as bronchitis and tonsillitis, as well as otitis media and certain urinary tract infections. Known for its stability against many beta-lactamases, ceftibuten is valuable in treating infections caused by beta-lactam-resistant strains. Its favorable pharmacokinetics and low side effect profile make it a reliable choice for outpatient therapy.

Reference

[1]. Wise, R., et al., Ceftibuten–in-vitro activity against respiratory pathogens, beta-lactamase stability and mechanism of action. J Antimicrob Chemother, 1990. 26(2): p. 209-13.