Cefuroxime Acid

For research use only. Not for therapeutic Use.

  • CAT Number: M013100
  • CAS Number: 55268-75-2
  • Molecular Formula: C16H16N4O8S
  • Molecular Weight: 424.39
  • Purity: ≥95%
Inquiry Now

Cefuroxime Acid(Cat No.:M013100)is a second-generation cephalosporin antibiotic effective against a broad range of bacterial infections. As the active form of cefuroxime, it inhibits bacterial cell wall synthesis, targeting gram-positive and gram-negative bacteria. Cefuroxime Acid is widely used in research and pharmaceutical applications, particularly in studies of bacterial resistance and drug development. It is stable against beta-lactamase enzymes, enhancing its effectiveness in treating resistant strains. This compound’s reliable antibacterial properties make it a valuable agent in microbiological and clinical research settings.


Catalog Number M013100
CAS Number 55268-75-2
Synonyms

cefaloxime;cefuroxim;ethyl)-7-((2-furanyl(methyoxyimino)acetyl)amino)-8-oxo-,(6r-(6-alpha,7-beta(z;(6r-(6alpha,7beta(z)))-3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic

Molecular Formula C16H16N4O8S
Purity ≥95%
Storage Room temperature
IUPAC Name (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1
InChIKey JFPVXVDWJQMJEE-IZRZKJBUSA-N
SMILES CO/N=C(/C1=CC=CO1)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Reference

1: Bertholee D, ter Horst PG, Hijmering ML, Spanjersberg AJ, Hospes W, Wilffert
B. Blood concentrations of cefuroxime in cardiopulmonary bypass surgery. Int J
Clin Pharm. 2013 Oct;35(5):798-804. doi: 10.1007/s11096-013-9810-z. Epub 2013 Jun
21. PubMed PMID: 23794078.
<br>

2: Christiansen IS, Kr&#248;igaard M, Mosbech H, Skov PS, Poulsen LK, Garvey LH.
Clinical and diagnostic features of perioperative hypersensitivity to cefuroxime.
Clin Exp Allergy. 2015 Apr;45(4):807-14. doi: 10.1111/cea.12455. PubMed PMID:
25395022.

<br>
3: Promelle V, Jany B, Drimbea A, Jezraoui P, Milazzo S. Tolerability of
intracameral cefuroxime during cataract surgery in case of penicillin allergy. J
Fr Ophtalmol. 2015 Apr;38(4):283-7. doi: 10.1016/j.jfo.2014.11.005. Epub 2015 Apr
1. PubMed PMID: 25840617.
<br>

4: Kulapina OI, Mikhailova MS. [Study on pharmacokinetics of cefuroxime by
dynamics of its distribution in oral fluid of patients with sinusitis]. Antibiot
Khimioter. 2014;59(9-10):29-32. Russian. PubMed PMID: 25975113.

<br>
5: Bookstaver DA, Bland CM, Woodberry MW, Mansell KB. Correlation of cefpodoxime
susceptibility with cephalothin and cefuroxime for urinary tract isolates. J Med
Microbiol. 2014 Feb;63(Pt 2):218-21. doi: 10.1099/jmm.0.063040-0. Epub 2013 Nov
8. PubMed PMID: 24214230.

<br>
6: Myneni J, Desai SP, Jayamanne DG. Reduction in postoperative endophthalmitis
with intracameral cefuroxime. J Hosp Infect. 2013 Aug;84(4):326-8. doi:
10.1016/j.jhin.2013.05.009. Epub 2013 Jul 5. PubMed PMID: 23834989.

<br>
7: Rodríguez-Caravaca G, García-Sáenz MC, Villar-Del-Campo MC, Andrés-Alba Y,
Arias-Puente A. Incidence of endophthalmitis and impact of prophylaxis with
cefuroxime on cataract surgery. J Cataract Refract Surg. 2013 Sep;39(9):1399-403.
doi: 10.1016/j.jcrs.2013.03.031. Epub 2013 Jun 29. PubMed PMID: 23820306.

Request a Quote