Centanafadine HCl

• CAT Number: I005934
• CAS Number: 923981-14-0
• Molecular Formula: C15H16ClN
• Molecular Weight: 245.75
• Purity: ≥95%
• Synonyms: EB-1020; EB 1020; EB1020; EB-1020 SR; CTN SR; Centanafadine;(1R,5S)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochoride
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: (1R,5S)-1-naphthalen-2-yl-3-azabicyclo[3.1.0]hexane;hydrochloride
• InChI: InChI=1S/C15H15N.ClH/c1-2-4-12-7-13(6-5-11(12)3-1)15-8-14(15)9-16-10-15;/h1-7,14,16H,8-10H2;1H/t14-,15+;/m1./s1
• InChIKey: ACVMJAJGCQUPKX-LIOBNPLQSA-N
• SMILES: C1[C@H]2[C@@]1(CNC2)C3=CC4=CC=CC=C4C=C3.Cl

Centanafadine HCl(CAT: I005934) is a triple monoamine reuptake inhibitor (TRI) that modulates the reuptake of dopamine, norepinephrine, and serotonin, with a preference for dopamine and norepinephrine. This pharmacological profile makes it a promising investigational compound for the treatment of attention-deficit/hyperactivity disorder (ADHD) and other neuropsychiatric disorders. By enhancing synaptic concentrations of these key neurotransmitters, Centanafadine HCl improves focus, attention, and executive function while potentially minimizing side effects associated with traditional stimulants. It is a valuable tool in research exploring the neurobiology of ADHD and the development of novel therapeutics targeting monoaminergic systems.