CEP-9722

• CAT Number: I005959
• CAS Number: 916574-83-9
• Molecular Formula: C24H26N4O3
• Molecular Weight: 418.50
• Purity: ≥95%
• Synonyms: CEP-9722; CEP 9722; CEP9722;11-methoxy-2-((4-methylpiperazin-1-yl)methyl)-4,5,6,7-tetrahydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione
• Target: Epigenetics
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• InChI: InChI=1S/C24H26N4O3/c1-26-9-11-27(12-10-26)13-28-23(29)18-14-5-3-6-15(14)22-20(21(18)24(28)30)19-16(25-22)7-4-8-17(19)31-2/h4,7-8,25H,3,5-6,9-13H2,1-2H3
• InChIKey: CTLOSZHDGZLOQE-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)CN2C(=O)C3=C4CCCC4=C5C(=C3C2=O)C6=C(N5)C=CC=C6OC

CEP-9722(CAT: I005959) is an orally bioavailable poly (ADP-ribose) polymerase (PARP) inhibitor that is primarily studied for its potential in cancer therapy. PARP enzymes play a critical role in DNA repair, and inhibiting them leads to the accumulation of DNA damage, ultimately causing cancer cell death, particularly in cells with BRCA1/2 mutations. CEP-9722 is of interest in research focused on enhancing the effectiveness of chemotherapy and radiotherapy by increasing the susceptibility of cancer cells to treatment. It is a valuable compound in exploring novel treatments for cancers with defective DNA repair mechanisms, such as ovarian and breast cancers.