For research use only. Not for therapeutic Use.
Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer’s disease[1].
| Catalog Number | I005962 |
| CAS Number | 925448-93-7 |
| Synonyms | N,N-dimethyl-3-[(3-naphthalen-1-ylsulfonyl-2H-indazol-5-yl)oxy]propan-1-amine |
| Molecular Formula | C22H23N3O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C22H23N3O3S/c1-25(2)13-6-14-28-17-11-12-20-19(15-17)22(24-23-20)29(26,27)21-10-5-8-16-7-3-4-9-18(16)21/h3-5,7-12,15H,6,13-14H2,1-2H3,(H,23,24) |
| InChIKey | NXQGEDVQXVTCDA-UHFFFAOYSA-N |
| SMILES | CN(C)CCCOC1=CC2=C(NN=C2C=C1)S(=O)(=O)C3=CC=CC4=CC=CC=C43 |
| Reference | [1]. Tse S, et al. Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry. Drug Metab Dispos. 2014;42(12):2023-2032. |
