Cetirizine HCl

• CAT Number: I005982
• CAS Number: 83881-52-1 (HCl)
• Molecular Formula: C21H27Cl3N2O3
• Molecular Weight: 461.81
• Purity: ≥95%
• Synonyms: AC-170; AC 170; AC170; HSDB 7739; HSDB7739; HSDB-7739; Cetirizine; trade names Zirtec, Zyrtec, Reactine; Cetryn; Setir; Virlix; Ziptek.;2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride
• InChI: InChI=1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
• InChIKey: PGLIUCLTXOYQMV-UHFFFAOYSA-N
• SMILES: C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

Cetirizine HCl(CAT: I005982) is a second-generation antihistamine widely utilized in pharmacological and clinical research. As a selective antagonist of H1 histamine receptors, it effectively inhibits histamine-mediated responses, such as allergic reactions and inflammation, without causing significant sedation. Cetirizine HCl is extensively studied for its efficacy in treating allergic rhinitis, urticaria, and other atopic conditions. Its high specificity and favorable pharmacokinetic profile make it ideal for exploring the mechanisms of histamine receptor antagonism and the development of antihistamine therapies. With high purity and stability, Cetirizine HCl is suitable for in vitro and in vivo research applications.