CFM-4

• CAT Number: I011115
• CAS Number: 331458-02-7
• Molecular Formula: C22H16ClN3OS
• Molecular Weight: 405.90
• Purity: ≥95%
• Synonyms: 1′-[(2-chlorophenyl)methyl]-5-phenylspiro[3H-1,3,4-thiadiazole-2,3′-indole]-2′-one
• IUPAC Name: 1'-[(2-chlorophenyl)methyl]-5-phenylspiro[3H-1,3,4-thiadiazole-2,3'-indole]-2'-one
• InChI: InChI=1S/C22H16ClN3OS/c23-18-12-6-4-10-16(18)14-26-19-13-7-5-11-17(19)22(21(26)27)25-24-20(28-22)15-8-2-1-3-9-15/h1-13,25H,14H2
• InChIKey: PMADITKBVODKSF-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=NNC3(S2)C4=CC=CC=C4N(C3=O)CC5=CC=CC=C5Cl

CFM-4（Cat No.:I011115）is a selective inhibitor of the protein kinase CK1δ (Casein Kinase 1 delta), an enzyme involved in regulating various cellular processes, including circadian rhythm, cell cycle progression, and DNA repair. By targeting CK1δ, CFM-4 modulates cellular functions, making it a potential therapeutic candidate for treating disorders linked to CK1δ dysregulation, such as cancer, neurodegenerative diseases, and sleep disorders. CFM-4 has shown promise in preclinical studies as an effective tool for investigating CK1δ’s role in cellular signaling and for developing targeted therapies aimed at controlling CK1δ activity.