cFMS Receptor Inhibitor IV

• CAT Number: I042673
• CAS Number: 959626-45-0
• Molecular Formula: C22H26N4O2
• Molecular Weight: 378.47
• Purity: ≥95%
• Synonyms: 5-cyano-N-[2,5-di(piperidin-1-yl)phenyl]furan-2-carboxamide
• InChI: InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27)
• InChIKey: FQGXFVDABCBEFW-UHFFFAOYSA-N
• SMILES: C1CCN(CC1)C2=CC(=C(C=C2)N3CCCCC3)NC(=O)C4=CC=C(O4)C#N

cFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM[1].

Reference

[1]. Patch RJ, et al. Potent 2′-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4.
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