For research use only. Not for therapeutic Use.
CGP 11130(CAT: I005966) is a potent and selective inhibitor of tyrosine kinases, particularly targeting epidermal growth factor receptor (EGFR) signaling pathways. Extensively used in cancer research, it disrupts EGFR-mediated cell proliferation, migration, and survival, making it valuable for exploring oncogenic signaling mechanisms. CGP 11130 is also employed in studies investigating resistance to EGFR inhibitors and in the development of combination therapies. Its high specificity and efficacy make it a critical tool for advancing the understanding of EGFR-related pathways and for driving innovation in targeted cancer therapeutics.
| Catalog Number | I005966 |
| CAS Number | 52237-19-1 |
| Synonyms | Cgp 11130; Cgp-11130; Cgp11130; Cgp-11.130.;Benzenepropanoic acid, beta-(aminomethyl)-4-fluoro- |
| Molecular Formula | C10H12FNO2 |
| Purity | 98% |
| Solubility | Soluble in DMSO, not in water |
| Appearance | Solid powder |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| Related CAS | 1858241-03-8(hydrochloride) |
| IUPAC Name | 4-amino-3-(4-fluorophenyl)butanoic acid |
| InChI | InChI=1S/C10H12FNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) |
| InChIKey | QWHXHLDNSXLAPX-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C(CC(=O)O)CN)F |
