For research use only. Not for therapeutic Use.
CGP 12177 ((±)-CGP 12177) hydrochloride is a β Adrenergic Receptor Ligand. CGP 12177 hydrochloride is a high affinity antagonist of β1- and β2-AR. CGP 12177 hydrochloride is also shown to interact, with a lower affinity, with the β3-AR and to exhibit a partial agonist activity on rodent and human β3-AR. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery[1].
CAS Number | 64208-32-8 |
Synonyms | 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one;hydrochloride |
Molecular Formula | C14H22ClN3O3 |
Purity | ≥95% |
InChI | InChI=1S/C14H21N3O3.ClH/c1-14(2,3)15-7-9(18)8-20-11-6-4-5-10-12(11)17-13(19)16-10;/h4-6,9,15,18H,7-8H2,1-3H3,(H2,16,17,19);1H |
InChIKey | YQVFCYCTITZLSX-UHFFFAOYSA-N |
SMILES | CC(C)(C)NCC(COC1=CC=CC2=C1NC(=O)N2)O.Cl |