For research use only. Not for therapeutic Use.
Cgp 38560 is a potent renin inhibitor.
| Catalog Number | I004927 |
| CAS Number | 122088-76-0 |
| Synonyms | Cgp 38560; Cgp38560; Cgp-38560.;L-Valinamide, N-(2-(((1,1-dimethylethyl)sulfonyl)methyl)-1-oxo-3-phenylpropyl)-L-histidyl-3-cyclohexyl-L-alanyl-N-butyl-, (R)-, monomethanesulfonate |
| Molecular Formula | C39H64N6O9S2 |
| Purity | ≥95% |
| Target | Renin Inhibitor |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4 °C for short term or -20 °C for long term |
| IUPAC Name | (2S)-N-[(2S)-2-amino-3-cyclohexylpropanoyl]-N-[(2S)-2-[[(2R)-2-benzyl-3-tert-butylsulfonylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]-2-(butylamino)-3-methylbutanamide;methanesulfonic acid |
| InChI | InChI=1S/C38H60N6O6S.CH4O3S/c1-7-8-19-41-33(26(2)3)37(48)44(35(46)31(39)21-28-17-13-10-14-18-28)36(47)32(22-30-23-40-25-42-30)43-34(45)29(20-27-15-11-9-12-16-27)24-51(49,50)38(4,5)6;1-5(2,3)4/h9,11-12,15-16,23,25-26,28-29,31-33,41H,7-8,10,13-14,17-22,24,39H2,1-6H3,(H,40,42)(H,43,45);1H3,(H,2,3,4)/t29-,31-,32-,33-;/m0./s1 |
| InChIKey | XXPFSPNMUAZMMO-CRNPUGFUSA-N |
| SMILES | CCCCNC(C(C)C)C(=O)N(C(=O)C(CC1CCCCC1)N)C(=O)C(CC2=CN=CN2)NC(=O)C(CC3=CC=CC=C3)CS(=O)(=O)C(C)(C)C.CS(=O)(=O)O |
| Reference | </br>1: Hanessian S, Claridge S, Johnstone S. The power of visual imagery in synthesis planning. Stereocontrolled approaches to CGP-60536B, a potent renin inhibitor. J Org Chem. 2002 Jun 14;67(12):4261-74. PubMed PMID: 12054962.</br></br> |
