CGP 55845

• CAT Number: I024468
• CAS Number: 150175-54-5
• Molecular Formula: C18H22Cl2NO3P
• Molecular Weight: 402.25
• Purity: 98%
• Synonyms: CGP 55845; CGP-55845; CGP55845
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid
• InChI: InChI=1S/C18H22Cl2NO3P/c1-13(15-7-8-17(19)18(20)9-15)21-10-16(22)12-25(23,24)11-14-5-3-2-4-6-14/h2-9,13,16,21-22H,10-12H2,1H3,(H,23,24)/t13-,16-/m0/s1
• InChIKey: ZODSPDOOCZZEIM-BBRMVZONSA-N
• SMILES: C[C@@H](C1=CC(=C(C=C1)Cl)Cl)NC[C@@H](CP(=O)(CC2=CC=CC=C2)O)O

CGP 55845（Cat No.:I024468）is a selective antagonist of the GABA-B receptor, a type of neurotransmitter receptor in the central nervous system. It has been primarily used in research to study the role of GABA-B receptors in various physiological processes, such as neurotransmission, pain modulation, and neurological disorders. By blocking the activity of GABA-B receptors, CGP 55845 can provide insights into how these receptors contribute to processes like anxiety, muscle spasticity, and seizures. While it holds potential for therapeutic applications, its use is primarily limited to experimental settings. Further studies are needed to explore its clinical implications.