For research use only. Not for therapeutic Use.
CGS-21680 hydrochloride (Cat.No:I012730) is a selective adenosine A2A receptor agonist. By activating the A2A receptor, CGS-21680 promotes vasodilation, inhibits platelet aggregation, and reduces inflammation. It has been studied for its potential use in the treatment of cardiovascular diseases, including ischemic heart disease and heart failure. CGS-21680 hydrochloride has also shown neuroprotective effects and has been investigated for its role in neurological disorders such as Parkinson’s disease.
| Catalog Number | I012730 |
| CAS Number | 124182-57-6 |
| Synonyms | 3-[4-[2-[[6-Amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin- 2-yl]amino]ethyl]phenyl]propanoic acid Hydrochloride |
| Molecular Formula | C23-H29-N7-O6 |
| Purity | ≥95% |
| InChI | 1S/C23H29N7O6/c1-2-25-21(35)18-16(33)17(34)22(36-18)30-11-27-15-19(24)28-23(29-20(15)30)26-10-9-13-5-3-12(4-6-13)7-8-14(31)32/h3-6,11,16-18,22,33-34H,2,7-10H2,1H3,(H,25,35)(H,31,32)(H3,24,26,28,29)/t16-,17+,18-,22+/m0/s1 |
| InChIKey | PAOANWZGLPPROA-RQXXJAGISA-N |
| SMILES | CCNC(=O)<wbr>[C@@H]1[C@H]([C@H]([C@@H](O1)<wbr>n2cnc3c2nc(nc3N)<wbr>NCCc4ccc(cc4)<wbr>CCC(=O)<wbr>O)<wbr>O)<wbr>O |
