CH-223191

• CAT Number: I003050
• CAS Number: 301326-22-7
• Molecular Formula: C₁₉H₁₉N₅O
• Molecular Weight: 333.39
• Purity: ≥95%
• Synonyms: 2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
• Target: Aryl Hydrocarbon Receptor
• Solubility: DMSO: ≥ 35 mg/mL
• Storage: Store at +4C
• InChI: InChI=1S/C19H19N5O/c1-13-6-4-5-7-17(13)23-22-15-8-9-16(14(2)12-15)21-19(25)18-10-11-20-24(18)3/h4-12H,1-3H3,(H,21,25)
• InChIKey: LKTNEXPODAWWFM-UHFFFAOYSA-N
• SMILES: CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C

CH-223191(CAT: I003050) is a potent and selective antagonist of the aryl hydrocarbon receptor (AhR), a transcription factor involved in xenobiotic metabolism, immune modulation, and developmental pathways. By inhibiting AhR activation, CH-223191 prevents the expression of downstream genes such as CYP1A1, which are induced by dioxins and other environmental toxins. This compound is widely utilized in studies exploring the role of AhR in toxicology, cancer, and immune system regulation. Its high specificity and consistent performance ensure reliable experimental outcomes, making it an essential tool for investigating AhR signaling pathways and potential therapeutic applications targeting this receptor.